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. 2021 Aug 2;12:662706. doi: 10.3389/fphar.2021.662706

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Copyright © 2021 Wang, Liu, Wang, Li, Liu, Tu, Yuan, Fang, Chen, Wang, Fu, Wan, Wan and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of SKI and ROS on the protein expression levels of Bax, Bcl-2, and caspase12, in vitro. (A) WB analysis of Bax, Bcl-2, and caspase12, in NRK-52E cells exposed to HG and 4-PBA with or without SKI or ROS for 24 h; (B–E) The rate of Bax, Bcl-2, and caspase12, to GAPDH, respectively, and the rate of Bax to Bcl-2. Data are expressed as mean ± S.E. *p < 0.05, **p < 0.01. Abbreviations: WB, Western blot; HG, high glucose; 4-PBA, 4-phenylbutyric acid; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; ROS, rosiglitazone; SKI, Shenkang injection.