Table 3.
Associations between psychiatric symptoms and oxysterols levels in schizophrenia patients.
| PANSS positive | PANSS negative | PANSS general | PANSS total | |||||
|---|---|---|---|---|---|---|---|---|
| t | P | t | P | t | P | t | P | |
| CHR INDIVIDUALS | ||||||||
| Age | −1.158 | 0.260 | 0.290 | 0.775 | −1.147 | 0.264 | −0.473 | 0.642 |
| Gender | −0.873 | 0.393 | −1.018 | 0.320 | 0.725 | 0.476 | −0.331 | 0.744 |
| Illness duration | −0.617 | 0.544 | 0.245 | 0.809 | −1.104 | 0.282 | −0.219 | 0.829 |
| Antipsychotics | 0.858 | 0.401 | −0.417 | 0.681 | 0.345 | 0.735 | 0.054 | 0.958 |
| Family history | −0.985 | 0.336 | 0.039 | 0.970 | −0.198 | 0.845 | −0.193 | 0.849 |
| 24OHC | 0.740 | 0.468 | 0.314 | 0.757 | −0.223 | 0.826 | −0.183 | 0.857 |
| 27OHC | −2.014 | 0.057 | −1.369 | 0.186 | −0.426 | 0.675 | −0.845 | 0.410 |
| SCZ PATIENTS | ||||||||
| Age | −1.816 | 0.074 | 0.080 | 0.936 | −0.757 | 0.452 | −0.961 | 0.340 |
| Gender | 3.046 | 0.003 | −0.262 | 0.794 | 1.510 | 0.136 | 1.649 | 0.104 |
| Illness duration | −0.665 | 0.509 | 0.251 | 0.803 | −0.517 | 0.607 | −0.329 | 0.743 |
| Antipsychotics | −1.536 | 0.130 | 0.068 | 0.946 | 0.794 | 0.430 | −0.125 | 0.901 |
| Family history | −0.477 | 0.635 | −1.532 | 0.131 | −0.921 | 0.361 | −1.564 | 0.123 |
| 24OHC | 0.505 | 0.615 | 1.976 | 0.053 | 1.407 | 0.164 | 2.084 | 0.041 |
| 27OHC | −2.310 | 0.024 | 0.904 | 0.370 | −0.301 | 0.764 | −1.531 | 0.131 |
SCZ, schizophrenia; CHR, clinically high risk; PANSS, Positive and Negative Syndrome Scale; 24OHC, 24(S)-hydroxycholesterol; 27OHC, 27-hydroxycholesterol.