Table 4.
ROC curve analysis of oxysterols in CHR participants and schizophrenia patients.
| AUC | Sensitivity | Specificity | 95% CI | |
|---|---|---|---|---|
| CHR individuals | ||||
| 24OHC | 0.591 | 0.525 | 0.692 | 0.488–0.695 |
| 27OHC | 0.537 | 0.505 | 0.667 | 0.436–0.638 |
| 24OHC and 27OHC | 0.592 | 0.525 | 0.692 | 0.488–0.696 |
| SCZ patients | ||||
| 24OHC | 0.618 | 0.683 | 0.526 | 0.534–0.701 |
| 27OHC | 0.681 | 0.485 | 0.842 | 0.603–0.759 |
| 24OHC and 27OHC | 0.767 | 0.782 | 0.671 | 0.697–0.837 |
SCZ, schizophrenia; CHR, clinically high risk; ROC, receiver operating characteristic; AUC, area under the ROC curve; CI, confidence interval; 24OHC, 24(S)-hydroxycholesterol; 27OHC, 27-hydroxycholesterol.