Table 1.
Demographic and Clinical Characteristics of Study Subjects
| Healthy (N=20) | Asthma (N=47) | p value | Asthma | |||
|---|---|---|---|---|---|---|
| Non-Allergy (N=20) | Allergy (N=27) | p value | ||||
| Age | 20.64±14.53 | 39.91±16.02 | 0.8604 | 42.7±17.44 | 37.85±14.88 | 0.3102 |
| Gender | >0.9999 | 0.513 | ||||
| Male | 10 | 22 | 12 | 10 | ||
| Female | 10 | 25 | 8 | 17 | ||
| Height (cm) | 163.2±8.36 | 161.3±7.96 | 0.3812 | 160.2±9.20 | 162.11±6.99 | 0.442 |
| Weight (kg) | 57.85±10.18 | 60.2±12.87 | 0.4709 | 58.48±11.46 | 61.48±13.90 | 0.4346 |
| BMI (kg/m2) | 21.58±2.39 | 23.09±4.42 | 0.1554 | 22.74±11.46 | 23.35±4.87 | 0.6497 |
| FEV1 (L) | 3.2±0.47 | 2.57±0.79 | 0.0007* | 2.49±0.83 | 2.64±0.76 | 0.5327 |
| FEV1%pred | 95.43±7.77 | 87.60±14.91 | 0.0301* | 87.46±13.24 | 87.71±16.28 | 0.9559 |
| FEV1/FVC | 90.565±3.94 | 80.47±9.83 | <0.0001* | 78.61±10.50 | 81.85±9.27 | 0.2677 |
| FENO (ppb) | 20.25±5.72 | 38.87±14.41 | <0.0001* | 31.3±10.16 | 44.48±14.66 | 0.0012* |
| EOS (*10E9/L) | 0.3485±0.14 | 0.42±0.33 | 0.3473 | 0.174±0.10 | 0.61±0.33 | <0.0001* |
| IgE (IU/mL) | (0–48, 27) | (0–531, 111) | 0.0005* | (0–142, 46) | (56–531, 213) | <0.0001* |
| IL-4 | 33.41±5.78 | 45.61±9.45 | <0.0001* | 37.3±6.80 | 51.77±5.62 | <0.0001* |
Notes: Data were presented by median (range) or mean ± standard deviation (x±s) (continuous). *p < 0.05.
Abbreviations: BMI, Body Mass Index; FEV1, forced expiratory volume in one second; FEV1%pred, FEV1/FEV1 prediction; FVC, Forced vital capacity; FENO, Fractional exhaled nitric oxide; EOS, Eosinophil; IgE, Immunoglobulin E; IL-4, Interleukin-4.