Table 1.
Baseline Characteristics of the Participants.
| Characteristic | Vaccine Group (N = 275)* | Placebo Group (N = 273)* | All Participants (N = 548) |
|---|---|---|---|
| Age — yr | |||
| Median | 30.0 | 29.0 | 29.0 |
| Range | 18–45 | 18–45 | 18–45 |
| Sex — % | |||
| Female | 22 | 23 | 22 |
| Male | 78 | 77 | 78 |
| Body-mass index† | |||
| Median | 24.4 | 24.3 | 24.3 |
| Range | 17.2–55.5 | 16.8–53.4 | 16.8–55.5 |
| Hispanic ethnic group — %‡ | 15 | 14 | 14 |
| Race or ethnic group — %‡ | |||
| American Indian or Alaska Native | 3 | <1 | 2 |
| Asian, Native Hawaiian, or Pacific Islander | 1 | 1 | 1 |
| Black or African American | 23 | 19 | 21 |
| White | 58 | 64 | 61 |
| Multiracial | 12 | 11 | 11 |
| Not reported | 3 | 4 | 4 |
| IFNL3 CC genotype — %§ | 41 | 41 | 41 |
One participant who had been randomly assigned to the placebo group was erroneously given vaccine for both doses and is classified within the vaccine group in all summaries and analyses.
The body-mass index is the weight in kilograms divided by the square of the height in meters.
Race and ethnic group were reported by the participants.
The IFNL3 CC genotype, which has been shown to enhance resolution of hepatitis C virus (HCV) infection,12 was determined from the rs12979860 single-nucleotide polymorphism.