Fig. 3.
Western blot showing the inducible expression of RhoA biosensor in MDA-MB231 tet-OFF cell line, detected using anti-RhoA GTPase antibody. Lane 1: Cell lysate from cell culture maintained with 2 μg/mL Dox; Lane 2: Cell lysate from biosensor induced cells that underwent single cycle of trypsinization; Lane 3: Cell lysate from biosensor induced cells that underwent two cycles of trypsinization. Endogenous RhoA expression levels are similar in all cases