Table 1.
Trial assessment timepoints.
| Study task or measurement performed | Screening or CVa1 | HVb1, 0 week | TCc1, 6-7 weeks | CV2, 12-13 weeks | TC2, 18-19 weeks | TC3, 24-26 weeks | TC4, 30 weeks | TC5, 36 weeks | TC6, 42 weeks | TC7, 48 weeks | TC8, 52 weeks | CV3, 76-78 weeks | HV2, 76-78 weeks |
| Patient information and consent | ✓d |
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| ISAACe questionnaires | ✓ |
|
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|
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|
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|
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| ACQ6f | ✓ |
|
✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
|
| AQLQg | ✓ |
|
✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
|
| RQLQh | ✓ |
|
✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
|
| Asthma history questionnairesi | ✓ |
|
✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
|
| Peak expiratory flow | ✓ | ✓ | ✓ | ✓ | ✓ |
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✓ | ✓ |
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| Physical examination | ✓ |
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✓ |
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✓ |
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| Skin prick test | ✓ |
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| Spirometry | ✓ |
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✓ |
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✓ |
|
| Bronchial challenge methacholine) | ✓ |
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✓ |
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| FeNOj | ✓ |
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✓ |
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✓ |
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| Dust sample collection |
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✓ |
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✓ | ✓ |
| Blood sample | ✓ |
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✓ |
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| Installation of air purifiers |
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✓ |
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| Indoor air pollution data by Dyson purifiers |
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✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Return of air purifiers |
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✓ |
| Letter to general practitioner | ✓ |
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✓ |
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aCV: center visit.
bHV: home visit.
cTC: telephone call.
dTask or measurement is performed.
eISAAC: International Study of Asthma and Allergies in Childhood.
fACQ6: Asthma Control Questionnaire 6.
gAQLQ: Asthma-Specific Quality of Life Questionnaire.
hRQLQ: Rhinoconjunctivitis Quality of Life Questionnaire.
iAsthma history questionnaire includes information on symptoms, medication use, and exacerbations in the past 2 weeks.
jFeNO: fractional exhaled nitric oxide.