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. 2021 Jul 30;9(7):e29840. doi: 10.2196/29840

Table 4.

Coefficient estimates, standard error, z-test statistics, and P values from pairwise linear mixed-effect models for exploring associations between Bluetooth features and the depressive symptom severity (8-item Patient Health Questionnaire).

Featurea Estimate SE z score Adjusted P valueb,c
Second-order statistics




Min_Max −0.052 0.012 −4.431 <.001

Mean_max −0.016 0.006 −2.809 .005

Max_Std −0.015 0.006 −2.657 .008

Min_Std −0.215 0.056 −3.838 <.001

Mean_Std −0.065 0.023 −2.802 .005

Std_Std −0.048 0.020 −2.385 .02

Max_Mean −0.030 0.008 −3.498 <.001

Min_Mean −0.093 0.046 −2.036 .04

Mean_Mean −0.083 0.026 −3.225 .001

Std_Mean −0.095 0.027 −3.464 .001
Multiscale entropy (MSE)

MSE_1 0.642 0.225 2.853 .005

MSE_2 0.433 0.192 2.255 .02

MSE_3 0.401 0.202 1.985 .04

MSE_16 −0.102 0.042 −2.429 .01

MSE_22 −0.123 0.043 −2.860 .005
Frequency domain (FD)

LFd_sum −0.021 0.005 −3.865 <.001
MFe_sum −0.067 0.014 −4.766 <.001

HFf_sum −0.027 0.010 −2.606 .009

MF_pctg −1.834 0.812 −2.259 .02

HF_seh 3.821 1.820 2.099 .04

aDefinitions of Bluetooth features in this table are shown in Table 1.

bOnly significant associations (adjusted P value <.05) are reported.

cP values were adjusted by the Benjamini-Hochberg method for correction of multiple comparisons.

dLF: low frequency (0-0.75 cycles/day).

eMF: middle frequency (0.75-1.25 cycles/day).

fHF: high frequency (>1.25 cycles/day).

gpct: percentage of spectrum power.

hse: spectral entropy.