Table 5.
Short-term clinical outcomes in the model-concordant and model-nonconcordant groups.
| Short-term outcomes |
Samples, n | Before adjustment | After propensity score weighting adjustment | ||||||||||
|
|
|
Incidence, n (%) | P value | ORa | 95% CI | P value | |||||||
| Antiglycemic treatmentb (HbA1c)c <7%) |
|
|
<.001 | 1.73 | 1.69-1.76 | <.001 | |||||||
|
|
Concordant | 78,670 | 48,263 (61.35) |
|
|
|
|
||||||
|
|
Nonconcordant | 99,819 | 21,507 (21.55) |
|
|
|
|
||||||
| Antihypertensive treatmentd (SBPe/DBPf<140/90 mmHg) |
|
|
<.001 | 1.26 | 1.23-1.29 | <.001 | |||||||
|
|
Concordant | 80,868 | 62,058 (76.74) |
|
|
|
|
||||||
|
|
Nonconcordant | 64,037 | 35,327 (55.17) |
|
|
|
|
||||||
| Lipid-lowering treatmentg (LDL-ch<2.6 mmol/L) |
|
|
<.001 | 1.28 | 1.22-1.35 | <.001 | |||||||
|
|
Concordant | 14,985 | 10,702 (71.42) |
|
|
|
|
||||||
|
|
Nonconcordant | 18,097 | 10,028 (55.41) |
|
|
|
|
||||||
| Antiglycemic treatmenti (Hypoglycemia in next 6 months) |
|
|
<.001 | 0.97 | 0.91-1.02 | 0.22 | |||||||
|
|
Concordant | 113,343 | 1497 (1.32) |
|
|
|
|
||||||
|
|
Nonconcordant | 148,405 | 3009 (2.03) |
|
|
|
|
||||||
aOR: odds ratio.
bConfounders considered: age, gender, ethnicity, smoking, duration of diabetes, HbA1c, SBP/DBP, LDL-c, triglycerides (TG), BMI, estimated glomerular filtration rate (eGFR), hypertension, hypercholesterolemia, macrovascular complication, microvascular complication, hypoglycemia history.
cHbA1c: glycated hemoglobin A1c.
dConfounders considered: age, gender, ethnicity, smoking, duration of diabetes, HbA1c, SBP/DBP, LDL-c, TG, BMI, eGFR, hypercholesterolemia, myocardial infarction, unstable angina, heart failure, stroke, nephropathy.
eSBP: systolic blood pressure.
fDBP: diastolic blood pressure.
gConfounders considered: age, gender, ethnicity, smoking, duration of diabetes, HbA1c, SBP/DBP, LDL-c, TG, BMI, eGFR, alanine transaminase, macrovascular complication, nephropathy.
hLDL-c: low-density lipoprotein cholesterol.
iConfounders considered: age, gender, ethnicity, smoking, duration of diabetes, HbA1c, SBP, LDL-c, BMI, serum creatinine, hypertension, atrial fibrillation, macrovascular complication, microvascular complication.