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(A) Measured optical attenuation coefficient error versus tissue surface position error. (B) Sensitivity or specificity reduces as the quantification error of the optical attenuation coefficient increases. An ∼ 0.5 mm of surface position error induced an optical attenuation coefficient error of ∼ 0.1 mm-1 and reduced sensitivity or specificity by ∼ 1% (as indicated by the red dashed lines).
