TABLE 2. Most frequent symptoms, signs, diagnostic results, and conditions* reported to the Vaccine Adverse Event Reporting System for adolescents aged 12–17 years after receipt of the Pfizer-BioNTech COVID-19 vaccine (N = 9,246) — United States, December 14, 2020–July 16, 2021.
| Symptom, sign, diagnostic result, or condition | % Reporting |
|---|---|
|
Nonserious reports (n = 8,383)
| |
| Dizziness |
21.2 |
| Syncope |
14.4 |
| Nausea |
10.4 |
| Headache |
10.0 |
| Fever |
8.3 |
| Loss of consciousness |
7.5 |
| Excessive sweating |
7.4 |
| Fatigue |
7.2 |
| Pallor |
7.1 |
| Product administered to patient outside of indicated age range |
7.0 |
| Product storage error |
6.4 |
| Vomiting |
6.4 |
| Difficulty breathing |
5.3 |
| Chest pain |
4.9 |
| Pain |
4.6 |
|
Serious reports, including reports of death†
(n = 863) | |
| Chest pain |
56.4 |
| Increased troponin |
41.7 |
| Myocarditis |
40.3 |
| Increased c-reactive protein |
30.6 |
| Negative SARS-CoV-2 test result |
29.4 |
| Fever |
28.3 |
| Normal echocardiogram |
26.9 |
| Abnormal electrocardiogram |
25.6 |
| Headache |
22.2 |
| Difficulty breathing |
21.4 |
| Elevated electrocardiogram ST segment |
20.5 |
| Normal chest radiograph |
19.7 |
| Intensive care |
18.1 |
| Vomiting |
17.0 |
| Nausea | 16.6 |
Abbreviations: MedDRA = Medical Dictionary for Regulatory Activities; VAERS = Vaccine Adverse Event Reporting System.
* Signs and symptoms in VAERS reports are assigned MedDRA preferred terms by VAERS staff members. Each VAERS report might be assigned more than one MedDRA preferred term, which can include normal diagnostic findings. A MedDRA-coded event does not indicate a medically confirmed diagnosis. https://www.meddra.org/how-to-use/basics/hierarchy
† VAERS reports are classified as serious if any of the following are reported: hospitalization, prolongation of hospitalization, life-threatening illness, permanent disability, congenital anomaly or birth defect, or death.