Table 2.
Comparison of RCTs across disease area (standard deviations are in parenthesis)
| Disease area | n | Number closed early | Award to start date in weeks (1998 onwards only) | % time extension | Publication identified* | % of intended recruitment achieved |
|---|---|---|---|---|---|---|
| Mental health | 21 | 0 | 52.7 (19.8) | 38.8 (38.9) | 20 | 71.1 (28.7) |
| Cancer | 19 | 1 | 56.2 (58.1) | 41.5 (40.3) | 17 | 90.3 (29.9) |
| Other | 106 | 7 | 52.3 (33.0) | 32.7 (32.9) | 97 | 86.1 (33.8) |
*The number of publications identified relates to the number of trials for which data of the originally planned and actual recruitment could be calculated as there was a key publication reporting the trial. For some later trials, the HTA monograph is still in preparation.