Table 5. Diagnostic yield of magnifying NBI applying UMEC for colonic lesions.
| Sensitivity % (95 % CI) | Specificity % (95 % CI) | PPV % (95 % CI) | NPV % (95 % CI) | Accuracy % (95 % CI) | Kappa value (95 % CI) P value | |
| C-UMEC 1 vs 2 + 3 (non-neoplastic vs neoplastic) | ||||||
| Endoscopist A | 89.4 (76.9–96.5) | 97.3 (90.6–99.7) | 95.5 (84.5–99.4) | 93.5 (85.5–97.9) | 94.2 (88.4–97.6) | 0.80 (0.69–0.90) P < 0.001 |
| Endoscopist B | 91.5 (79.6–97.6) | 100 (92.8–100) | 100 (88.0–100) | 94.9 (87.4–98.6) | 96.7 (91.8–99.1) | |
| C-UMEC 1 + 2A vs 2B + 3 (non-cancer vs cancer) | ||||||
| Endoscopist A | 76.1 (61.2–87.4) | 77.2 (66.4–85.9) | 66.0 (51.7–78.5) | 84.7 (74.3–92.1) | 76.8 (68.4–83.9) | 0.63 (0.49–0.77) P < 0.001 |
| Endoscopist B | 82.6 (68.6–92.2) | 93.7 (85.8–97.9) | 88.4 (74.9–96.1) | 90.2 (81.7–95.7) | 89.6 (82.9–94.3) | |
| C-UMEC 1 + 2 vs 3 (Deep submucosal invasive cancer vs others) | ||||||
| Endoscopist A | 91.3 (72.0–98.9) | 95.1 (88.9–98.4) | 80.8 (60.6–93.4) | 98.0 (92.9–99.8) | 94.4 (88.8–97.7) | 0.66 (0.48–0.83) P < 0.001 |
| Endoscopist B | 69.6 (47.1–86.8) | 100 (94.7–100) | 100 (71.3–100) | 93.6 (87.2–97.4) | 94.4 (88.8–97.7) | |
NBI, narrow-band imaging; UMEC, unified magnifying endoscopic classification; PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval.