Figure 4.

The effect of AM on the expression of the NLRP3 inflammasome and the β-arrestin1 signaling pathway in mice with DSS-induced colitis. The protein expression levels of NLRP3, ASC, caspase 1 p10, IL-1β, and IL-18 (a) in colonic tissue were measured by western blotting. The protein expression levels of NLRP3 (b), ASC (c), caspase 1 p10 (d), IL-1β (e), and IL-18 (f) were quantitated by Image software. The data are presented as the mean ± SEM. ^∗∗P < 0.01, compared to the normal group; ^#P < 0.05 and ^##P < 0.01, compared to the model group.