Table 2.

Inhibitors showing binding affinities against active sites of target proteins.

			RdRp		Mpro		Spike glycoprotein
Sr. #	Ligand	PubChem ID	Energy score (kcal/mol) (MOE) Molecular Operating Environment	Binding Affinity (KD) Dissociation Constant (Discovery studio)	Energy score (kcal/mol) (MOE)	Binding Affinity (KD) (Discovery studio)	Energy score (kcal/mol) (MOE)	Binding Affinity (KD) (Discovery studio)
1	Teprotide	443,376	−7.25	−9.7	−10.95	−12.4	−6.95	−10.9
2	Moexipril	91,270	−10.27	−13.5	−7.55	−7.1	−5.93	−7.3
3	Cilazapril	56,330	−9.03	−9.8	−7.99	−7.9	−6.35	−7.9
4	Benazepril	5,362,124	−8.97	−8.9	−8.88	−9.0	−6.34	−7.9
5	Trandolapril	5,484,727	−6.76	−8.7	−8.04	−8.4	−6.93	−8.0
6	Quinapril	54,892	−7.74	−8.5	−8.45	−8.7	−6.32	−7.7
7	Lisinopril	5,362,119	−8.36	−8.1	−6.01	−6.7	−5.48	−6.5
8	Enalapril	5,388,962	−8.50	−8.0	−7.77	−7.7	−5.94	−7.3
9	Ramapril	121,486,657	−8.34	−8.0	−6.17	−6.9	−6.31	−7.7
10	Perindopril	107,807	N/A	−6.8	−7.13	−6.9	−6.02	−7.4
11	Captopril	44,093	−5.40	−6.5	−6.00	−6.2	−5.34	−6.5
12	Allicin	65,036	No interaction	−4.9	−5.90	−4.7	−5.21	−4.9