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. 2021 Aug 17;36(10):109664. doi: 10.1016/j.celrep.2021.109664

Figure 4.

Figure 4

Immune protection of spike- and nucleocapsid-based vaccines

RNA was harvested from the lungs (A) and brains (B) at 72 h post-infection, and viral RNA was quantified by qRT-PCR.

Challenges were performed with a total of 5 mice per group in biosafety level 3 (BSL-3) facilities. Error bars represent SEMs. Indicated p values were calculated using Kruskal-Wallis test (Dunn’s multiple comparisons). NS, not significant (p > 0.05).