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Risk of bias assessment for RCTs. The Cochrane Risk of Bias tool was used to assess potential sources of bias in included RCTs, rating each as low, high, or unclear risk of bias. ‘Yes’ indicates the Cochrane RoB domain is satisfied, and presents a low risk of bias; ‘No’ indicates the Cochrane RoB domain is not satisfied and may present a high risk of bias; ‘Unclear’ indicates that insufficient information was presented to determine risk of bias.
