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. 2021 May 24;101(9):1197–1209. doi: 10.1038/s41374-021-00610-9

Fig. 4. AOPPs activated the IKK/IκB/NF-κB pathway in vitro and in vivo.

Fig. 4

AOPPs increased the expression of p-NF-κB, p-IKBα, and p-IKKα/β in the total protein fraction of HepG2 and L-02 cells (A). AOPPs increased the expression of p-NF-κB, p-IKBα, and p-IKKα/β in the liver tissues of the sham and 5/6 nx groups (B). Protein expression levels were quantified by ImageJ software (C, D). Each experiment was performed with a different isolate. Data are presented as mean ± SD; *p < 0.05 compared with the CON or PBS groups. Data were normalized to GAPDH.