Table II.
Multiple Stages Temperature Validation 37°C of the 3D-Printed Disintegration Vessel When Loaded with 0.05 or 0.7 mL of PBS and During the Disintegration Process of Nurofen Meltlet. ± Symbol Represents Standard Deviation Between Measurements, over 250 s with Temperature Reading Frequency of 1 Reading/s. Each Temperature Was Validated Three Times.
| Temperature validation | The mean temperature at the start (°C) | Mean temperature at the end (°C) ± Standard deviation (°C) |
|---|---|---|
| 3D-printed kit with 0.05 mL PBS at 37°C | 37.52 ± 0.00 | 37.51 ± 0.00 |
| 3D-printed kit with tablet and 0.05 mL PBS at 37°C | 36.56 ± 0.00 | 37.47 ± 0.05 |
| 3D-printed kit with 0.7 mL PBS at 37°C | 36.94 ± 0.00 | 36.93 ± 0.05 |
| 3D-printed kit with tablet and 0.7 mL PBS at 37°C | 37.13 ± 0.42 | 37.44 ± 0.09 |
PBS, phosphate buffer saline