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. 2021 Aug 16;22(7):219. doi: 10.1208/s12249-021-02080-0

Table II.

Multiple Stages Temperature Validation 37°C of the 3D-Printed Disintegration Vessel When Loaded with 0.05 or 0.7 mL of PBS and During the Disintegration Process of Nurofen Meltlet. ± Symbol Represents Standard Deviation Between Measurements, over 250 s with Temperature Reading Frequency of 1 Reading/s. Each Temperature Was Validated Three Times.

Temperature validation The mean temperature at the start (°C) Mean temperature at the end (°C)
± Standard deviation (°C)
3D-printed kit with 0.05 mL PBS at 37°C 37.52 ± 0.00 37.51 ± 0.00
3D-printed kit with tablet and 0.05 mL PBS at 37°C 36.56 ± 0.00 37.47 ± 0.05
3D-printed kit with 0.7 mL PBS at 37°C 36.94 ± 0.00 36.93 ± 0.05
3D-printed kit with tablet and 0.7 mL PBS at 37°C 37.13 ± 0.42 37.44 ± 0.09

PBS, phosphate buffer saline