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Summary of factors regulating the expression of Smad7. Smad7 can be regulated at both the transcriptional and posttranscriptional levels. A variety of transcription factors (TFs) regulate the expression of Smad7 at the transcriptional level. The regulation factor of Smad7 post-transcription involves ubiquitination, deubiquitylation, acetylation, deacetylation, methylation, miRNAs, and lncRNAs
