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. 2021 Aug 16;11:16579. doi: 10.1038/s41598-021-95891-x

Figure 4.

Figure 4

Inhibition of chimeric VLP binding through a silencing of EGFR by siRNA or interference with GE-11 peptide. SW480 cells were treated with siRNA against EGFR (A) or with GE11 peptide (B) prior to incubation with chimeric Mr-NV-VLPs and quantified the binding by flow cytometric analyses. Controls were SW480 cells treated with siRNA against luciferase (A, siLuc) or scramble peptide (B). * and ** denote statistical differences at p < 0.05 and 0.01, respectively (Student’s t test, n = 3, graphs represent mean ± SEM).