Table 1.
Overall survival | Recurrence-free survival | |||||
---|---|---|---|---|---|---|
Characteristic | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p |
n = 100 OSCC patients | ||||||
MCL-1 expression | ||||||
Low | 1 | 1 | ||||
High | 2.572 | 1.245–5.313 | 0.008** | 2.323 | 1.153–4.679 | 0.015* |
USP9X expression | ||||||
Low | 1 | 1 | ||||
High | 2.281 | 1.134–4.590 | 0.017* | 2.05 | 1.041–4.039 | 0.034* |
Lymph node | ||||||
No | 1 | 1 | ||||
N+ | 2.639 | 1.211–5.749 | 0.015* | 2.788 | 1.283–6.057 | 0.01* |
Site of primary tumour | ||||||
Tounge | 1 | 1 | ||||
Alveolus | 2.478 | 0.971–6.321 | 0.058 ns | 2.411 | 0.945–6.150 | 0.066 ns |
Buccal mucosa | 2.553 | 1.200–5.432 | 0.015* | 2.659 | 1.257–5.625 | 0.011* |
T stage | ||||||
T1-T2 | 1 | 1 | ||||
T3-T4 | 2.485 | 0.765–8.075 | 0.13 | 2.58 | 0.795–8.374 | 0.115 ns |
Differentiation status | ||||||
Moderate-well | 1 | 1 | ||||
Poor | 1.774 | 0.936–3.360 | 0.079 | 1.936 | 1.033–3.626 | 0.039* |
Combination MCL-1/USP9X | ||||||
Any low MCL-1/USP9X | 1 | 1 | ||||
Both MCL-1/USP9X High | 3.241 | 1.543–5.657 | 0.005** | 3.022 | 1.451–5.193 | 0.011* |
p > 0.05 ns not significant.
*p < 0.05.
**p < 0.01.