Table 2.
Phase | # compounds | % | Enhancer | Inhibitor |
---|---|---|---|---|
Maybridge Library | 24,000 | 100 | NA | NA |
Primary | 2160 | 9 | 1958 | 202 |
Primary confirmation | 232 | 0.97 | 148 | 84 |
Secondary | 41 | 0.17 | 3 | 39 |
Secondary confirmation | 23 | 0.1 | 0 | 23 |
Passed med chem filters | 16 | 0.07 | 0 | 16 |
Retest reordered drugs | 5 | 0.02 | 0 | 5 |
GFP-RFP-LC3 HeLa | 5 | 0.02 | 0 | 5 |
LC3II western blot | 2 | 0.01 | 0 | 2 |