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. 2021 Jul 23;297(3):101003. doi: 10.1016/j.jbc.2021.101003

Table 2.

Summary of Maybridge screen and orthogonal autophagic flux assays

Phase # compounds % Enhancer Inhibitor
Maybridge Library 24,000 100 NA NA
Primary 2160 9 1958 202
Primary confirmation 232 0.97 148 84
Secondary 41 0.17 3 39
Secondary confirmation 23 0.1 0 23
Passed med chem filters 16 0.07 0 16
Retest reordered drugs 5 0.02 0 5
GFP-RFP-LC3 HeLa 5 0.02 0 5
LC3II western blot 2 0.01 0 2