Table 1.
Characteristics of analysis population.
| All (n = 4516) | |
|---|---|
| Age (years)* [nmiss = 0] | 59.6 ± 7.8 |
| Female Sex# | 2256 (50.0%) |
| Serum lipid concentration (mg/dl)* | |
| HDL-C [nmiss = 1] | 58.16 ± 17.29 |
| LDL-C [nmiss = 14] | 145.41 ± 36.21 |
| TC [nmiss = 0] | 229.26 ± 39.18 |
| Lipid-lowering medication [nmiss = 289]# | 557 (13.2%) |
| Number of lipid effect alleles (GESLipid§)* | |
| GESHDL-C [nmiss = 0] | 78.3 ± 5.1 |
| GESLDL-C [nmiss = 0] | 55.1 ± 4.5 |
| GESTC [nmiss = 0] | 75.7 ± 5.2 |
| Number of lipid effect alleles (GESLipid-EXT+)* | |
| GESHDL-C-EXT [nmiss = 0] | 136.4 ± 6.6 |
| GESLDL-C-EXT [nmiss = 0] | 93.6 ± 5.9 |
| GESTC-EXT [nmiss = 0] | 126.2 ± 6.6 |
| Education (years of training)# [nmiss = 13] | |
| ≤ 10 | 515 (11.4%) |
| 11–13 | 2502 (55.6%) |
| ≥ 14 | 1486 (33.0%) |
| Income (€/month) † [nmiss = 283] | 1448.7 (1107.8–1874.7) |
| Body mass index (kg/m2)* [nmiss = 25] | 27.92 ± 4.64 |
| No physical activity# | 2302 (51.0%) |
| Current smoking# [nmiss = 7] | 1069 (23.7%) |
| Alcohol consumption† (g/week) [nmiss = 112] | 13.9 (0–64.5) |
| Diabetes mellitus # | 615 (13.6%) |
nmiss = number of participants with missing values, HDL-C = high-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol, TC = total cholesterol, GES = genetic effect allele sum score, diabetes mellitus is defined as self-reported diabetes mellitus, or fasting blood glucose level ≥ 126 mg/dl or postprandial blood glucose level ≥ 200 mg/dl or if the use of anti-diabetic medication was documented.
*Mean ± standard deviation (SD)
#Proportion (%)
†Median (first quartile-third quartile)
§GESLipid based on14