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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Curr Opin Chem Biol. 2021 Feb 18;64:1–9. doi: 10.1016/j.cbpa.2021.01.003

Figure 3.

Figure 3.

Cellular uptake of the Aβ peptides studied by flow cytometry. (A) Sequence of the mirror-image peptide pair (MIPP) Aβ peptides tested. (B) Mean FACS results in SH-SY5Y cells normalized against L-Aβ40 (5 μM peptide, 15 h incubation). Bars show mean fluorescence with error bars for SD of three biological replicates. (C) Mean FACS results in HEK293T cells with and without PrPC expression, normalized against L-Aβ40 (5 μM peptide, 2 h incubation). Bars show mean fluorescence with error bars for SD of two biological replicates. Image reproduced with permission from Proc. Natl. Acad. Sci. U S A 2020, 117 (46), 28625–28631