Figure 7.

Potential small-molecule compounds based on ferroptosis score

(A) Volcano plot depicted the down- (green) and upregulated (red) genes between the high and low ferroptosis score groups. (B) Heatmap visualized the differences in expression patterns of DEGs between the two groups. (C) GO enrichment analysis of biological process (BP), cellular component (CC), and molecular function (MF) results ranked by adjusted p value. (D) KEGG pathway enrichment analysis results showed these pathways and enriched genes. (E) Heatmap showed small-molecule compounds (perturbagen) and their shared drug mechanisms of action (rows) through the CMap database.