Figure 7.

Angiotensin II promoted the activation of NLRP3 inflammasome in human NP cells in vitro. (a) Immunofluorescence results for the expression of NLRP3 in human NP cells induced by Ang II, n = 3. Scale bar = 50 μm. (b) Ang II promoted the secretion of inflammation-related cytokines in human NP cells (n = 3). (c) The effects of Ang II on the expression of NLRP3 inflammasome-related proteins and inflammatory mediators in human NP cells (n = 3). (d) The results of western blot were quantified as graphs (n = 3). p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001.