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. 2021 Aug 3;13:675016. doi: 10.3389/fnagi.2021.675016

Table 5.

Z-scores and the differences between the observed volumes and the predicted volumes.

Before ethnicity adjustment After ethnicity adjustment
Kor.CN Cau.CN Kor.CN Cau.CN
z t p z t p z t p z t p
Brain 0.24 1.59 0.113 −0.58 −3.11 0.002 −0.02 −0.12 0.901 −0.02 0.35 0.728
Cortical gray matter 0.18 1.37 0.171 −0.62 −4.15 0.000 −0.14 −1.03 0.304 0.04 0.59 0.555
   Frontal L 0.08 0.67 0.502 −0.37 −2.83 0.005 −0.13 −1.10 0.270 0.08 0.56 0.574
   Frontal R 0.12 0.99 0.321 −0.39 −3.37 0.001 −0.11 −0.91 0.365 0.10 0.37 0.710
   Temporal L 0.20 1.75 0.080 −0.61 −3.93 0.000 −0.08 −0.70 0.482 −0.01 1.27 0.204
   Temporal R 0.19 1.57 0.117 −0.56 −3.76 0.000 −0.08 −0.75 0.453 0.01 1.04 0.297
   Parietal L 0.17 1.45 0.149 −0.71 −5.43 0.000 −0.16 −1.30 0.196 −0.06 0.29 0.771
   Parietal R 0.18 1.59 0.112 −0.69 −5.17 0.000 −0.15 −1.11 0.268 −0.04 0.32 0.745
   Occipital L 0.12 0.97 0.333 −0.34 −3.20 0.001 −0.06 −0.81 0.419 0.06 0.54 0.588
   Occipital R 0.11 1.05 0.294 −0.34 −2.62 0.009 −0.05 −0.47 0.636 0.00 0.44 0.662
   Cingulate L 0.11 1.09 0.278 −0.30 −2.48 0.014 −0.01 −0.12 0.901 −0.03 −0.13 0.898
   Cingulate R 0.07 0.70 0.482 −0.33 −3.99 0.000 −0.11 −1.25 0.212 0.06 0.14 0.885
   Insular L 0.18 2.01 0.046 −0.31 −3.50 0.001 0.00 0.05 0.959 0.09 0.29 0.775
   Insular R 0.21 2.44 0.015 −0.40 −4.88 0.000 0.00 0.07 0.945 0.08 −0.09 0.932
Subcortical gray matter 0.16 1.53 0.127 −0.33 −3.19 0.002 0.03 0.31 0.754 −0.03 −0.42 0.672
   Thalamus L 0.25 2.90 0.004 −0.58 −8.17 0.000 0.00 −0.31 0.756 −0.04 −0.95 0.344
   Thalamus R 0.28 2.97 0.003 −0.56 −7.53 0.000 0.02 −0.14 0.890 0.00 −1.02 0.307
   Putamen L −0.08 −0.53 0.598 0.13 2.45 0.015 0.01 0.58 0.563 −0.05 −0.13 0.897
   Putamen R 0.00 0.19 0.848 0.20 1.64 0.103 0.07 1.06 0.288 0.06 −0.12 0.901
   Hippocampus L 0.19 2.21 0.028 −0.25 −2.73 0.007 0.06 0.58 0.564 0.06 0.74 0.457
   Hippocampus R 0.21 2.16 0.031 −0.34 −3.81 0.000 0.05 0.40 0.689 0.04 0.45 0.650
   Caudate L 0.01 0.43 0.670 −0.19 −1.35 0.178 −0.03 0.04 0.970 −0.11 −0.34 0.737
   Caudate R −0.08 −0.65 0.517 0.20 2.96 0.003 0.05 0.76 0.450 −0.07 −0.12 0.902
   Amygdala L 0.13 1.05 0.293 −0.20 −1.23 0.219 0.04 0.20 0.843 0.00 0.92 0.360
   Amygdala R 0.08 0.45 0.657 −0.17 −1.45 0.148 0.00 −0.48 0.628 0.03 0.77 0.442
   Pallidus L 0.03 0.55 0.580 −0.06 −2.20 0.029 −0.02 −0.10 0.923 0.02 −1.05 0.297
   Pallidus R 0.15 1.94 0.053 −0.22 −3.21 0.001 0.04 0.48 0.628 0.02 0.29 0.769
   Accumbens L −0.15 −1.61 0.108 0.40 5.73 0.000 0.03 0.81 0.419 0.02 1.29 0.199
   Accumbens R −0.21 −2.00 0.047 0.48 4.45 0.000 −0.02 0.28 0.777 0.07 −0.05 0.964
   Ventral diencephalon L 0.09 1.13 0.261 −0.23 −1.88 0.061 −0.01 0.09 0.930 0.00 0.32 0.751
   Ventral diencephalon R 0.08 0.93 0.355 −0.10 −1.47 0.143 0.02 0.33 0.739 0.05 −0.11 0.912
Stem 0.08 0.95 0.344 −0.03 0.18 0.859 0.06 0.76 0.450 0.03 0.76 0.450
Corpus callosum 0.11 1.35 0.179 −0.06 −1.02 0.307 0.04 0.45 0.656 0.10 0.97 0.332
Ventricle −0.05 −0.78 0.438 0.00 0.34 0.731 −0.07 −0.96 0.335 0.02 0.56 0.577
   Lateral L −0.03 −0.61 0.542 0.00 0.00 0.997 −0.06 −0.91 0.365 0.05 0.42 0.673
   Lateral R −0.07 −0.94 0.346 0.04 1.11 0.266 −0.07 −0.90 0.366 0.02 0.87 0.387
   Inferior lateral L −0.07 −0.82 0.414 −0.11 −0.85 0.398 −0.11 −1.26 0.210 −0.02 0.10 0.922
   Inferior lateral R −0.08 −0.99 0.325 −0.08 −0.43 0.665 −0.09 −1.07 0.284 −0.07 −0.45 0.654
   3rd 0.08 0.71 0.480 −0.33 −3.44 0.001 −0.06 −0.60 0.546 −0.03 −0.45 0.652
   4th −0.06 −0.73 0.469 −0.20 −1.73 0.084 −0.10 −1.35 0.177 −0.09 −0.47 0.636

The z scores with p < 0.00125 are presented in bold and italic. The scores with p < 0.05 are presented in bold. L, left; R, right. Kor, Korean; Cau, Caucasian; CN, normal controls.