. Author manuscript; available in PMC: 2022 Jun 2.

Published in final edited form as: J Am Chem Soc. 2021 May 20;143(21):8193–8207. doi: 10.1021/jacs.1c03572

Table 2.

The mass differences for the proposed adducts between theoretical and experimental mass values of native/modified hOAT observed in native MS.

Samples	Theoretical mass difference (per monomer, Da)	Experimental mass (dimer, Da)	Experimental mass difference (per monomer, Da)

Native hOAT	231.0	92736.6 ± 1.8	230.8
hOAT- gabaculine	368.1	93014.8 ± 1.5	369.9
hOAT-11b	366.1	93009.2 ± 1.0	367.1
hOAT-14	414.1 (28 in pathway a1)	93031.6 ± 0.9	378.3
	396.1 (30 in pathway a2)
	378.1 (32 in pathway a3)
	418.1 (35 in pathway b)