Table 1.
Potential stress mediators in human endometrium.
| Stress gene | Location and phase of present | Potential function | References |
|---|---|---|---|
| BDNF | Human endometrium | Regulate endometrial cells proliferation | (23) |
| NR3C1 | Uterine epithelial cell line | Immune cell trafficking and embryonic development | (24) |
| NPY | Decidua | Immunoreactive of fetal membranes | (25) |
| HSPA5 | Human endometrium | Response the paracrine and autocrine factors | (26) |
| MAPK | Human endometrium | Immunomodulatory, regulate stress adaptation and endometrial remodeling | (27) |
| PAR2 | Human endometrium | Endometrial remodeling | (28) |
| NET | Late proliferative epithelium | Decidualization | (23, 29) |
| EMT | Secretory stroma | Decidualization | (23, 29) |
| VMAT2 | Proliferative stroma and secretory epithelium | Proliferation and decidualization | (23, 29, 30, 31) |
| PMAT | Proliferative stroma | Stromal proliferation | (23, 29, 30, 31) |
| PNMT | Human endometrium | Uterine activity during pregnancy and parturition | (22, 32) |
| COMT | Human endometrial stroma | Inhibit endometrial stroma cell proliferation | (22, 33) |
| MAO-A | Human endometrium | Embryo implantation and endometrial receptivity | (34, 35) |
| MAO-B | Human endometrium | Endometrial receptivity | (34) |
| ADRA2C | Human endometrium | Unclear | (36) |
| Opioid receptor | Human endometrium | Proliferation and decidualization | (37, 38) |