Figure 3.

Scheme of the potential of miRNAs in personalized prostate cancer. MiRNAs are present in biological samples, which could be a useful tool for diagnosis and staging in the first consult, allowing an accurate risk stratification. Based on information collected, the treatment can be planned. Treatments can be personalized according to radioresistance or radiosensitive of cancer. If cancer is radioresistance, radical prostatectomy is the therapeutic approach more indicated. Otherwise, RT is ideal treatment to apply to radiosensitive tumors. Also, miRNA signature can give information about the risk of develop side effects or if the patient is responding or not to treatment, leading to a better tumor control with reduced side effects, which contribute to a better patient quality life.