Figure 4.

Scheme illustrates different microRNA therapy approaches – anti-microRNA therapy (A) and mimicking microRNA therapy (B) to change miRNA-regulated gene expression. In therapy (A) the microRNA inhibitors are transfected to cells and suppressing onco-microRNA functions and consequently increased protein production. In contrast, in therapy (B) are introduced microRNA mimetics to target cells where interact with tumor suppressor microRNA target, suppressing of protein production.