Table 1. MIC Values (μg/mL) of C5α-Substituted Carbapenem Antibiotics against Mtb and Mab^a.

	Mtb		Mab
carbapenem	alone	with clavulanate (5 μg/mL)	alone	with avibactam# (5 μg/mL)
meropenem*	1.1	0.5	2.6	3.1
10a	0.1	0.1	0.4	0.5
10b	2.1	1.6	22.3	11.6
13a	0.8	0.6	7.5	5.8
13b	7.9	5.6	NA	NA

^aNA: No activity at the highest conc. (30.3 μg/mL). *P < 0.05, comparison of +/- clavulanate. ^#No statistical difference with +/- avibactam.