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Osteosarcoma H-scores in the cytoplasm and nucleus following immunohistochemical staining. Average H-scores for (A) GLUT1, (B) MMP3, and (C) NRF2. H-score distributions across samples for (D) GLUT1 (P > 0.05), (E) MMP3 (****P < 0.0001), and (F) NRF2 (**P = 0.008). Differences between nuclear and cytoplasmic staining were assessed using chi-square.
