Table 4. . Breakdown of healthcare costs of the overall study population and study cohorts during the follow-up per patient per month.

Healthcare resource category	Overall study population	Ablative therapy	Embolization therapy	Radiation therapy	Multiple LRTs	p-value
All-cause
Total healthcare cost	$20,316 ($26,447)	$11,401 ($13,762)	$20,010 ($21,208)	$20,901 ($31,023)	$30,417 ($42,402)	< 0.001
Total patient OOP cost	$378 ($691)	$287 ($476)	$380 ($643)	$390 ($789)	$457 ($937)	0.013
Inpatient medical service cost	$5675 ($19,489)	$4359 ($10,146)	$5944 ($14,271)	$7090 ($25,283)	$5357 ($34,003)	0.404
Outpatient medical service cost	$12,762 ($17,820)	$4930 ($6823)	$12,118 ($15,257)	$12,936 ($17,742)	$23,142 ($27,046)	< 0.001
Outpatient pharmacy cost	$1878 ($5425)	$2112 ($5519)	$1948 ($5714)	$875 ($3957)	$1919 ($4884)	0.068
HCC related
Total medical cost	$14,359 ($23,064)	$6111 ($9121)	$14,332 ($18,037)	$11,565 ($15,938)	$24,564 ($41,283)	< 0.001
Total HCC-related patient OOP medical cost	$227 ($565)	$136 ($294)	$228 ($503)	$213 ($641)	$324 ($855)	< 0.001
Inpatient medical service cost	$4160 ($16,966)	$3204 ($8196)	$4657 ($12,146)	$2542 ($8068)	$4260 ($33,650)	0.278
Outpatient medical service cost	$10,199 ($16,455)	$2908 ($4141)	$9674 ($14,068)	$9023 ($13,987)	$20,304 ($26,005)	< 0.001

All cost data are reported as means with standard deviations in 2019 USD. p-values are for the comparisons across all study cohorts.

HCC: Hepatocellular carcinoma; LRT: Locoregional therapy; OOP: Out of pocket; PPPM: Per patient per month.