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Linear Purkinje cell densities in control dogs (Ct) and dogs with Mucopolysaccharidosis IIIB (IIIB) were calculated at each time point in four regions of the cerebellum. Mean linear cell density is decreased in three of the four examined regions of the cerebellum at 4 months of age and decreased in all examined regions at 10 months of age. Loss of Purkinje cells were not observed in any control dogs. Data are shown as mean ± SEM.
