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. 2021 Jun 30;59(238):604–607. doi: 10.31729/jnma.5700
The International Classification of Headache Disorders (ICHD) criteria for THS include the following:7
A. Unilateral headache fulfilling criterion C
B. Both of the following:
  1. granulomatous inflammation of the cavernous sinus, superior orbital fissure or orbit, demonstrated by MRI or biopsy
  2. paresis of one or more of the ipsilateral IIIrd, IVth, and/or VIth cranial nerves
C. Evidence of causation demonstrated by both of the following:
  1. headache has preceded paresis of the IIIrd, IVth, and/or VIth nerves by ≤2 weeks, or developed with it
  2. headache is localized around the ipsilateral brow and eye
D. Not better accounted for by another ICHD-3 diagnosis.