Table 3.
Secondary outcomes: Change from Baseline (B) to 6 month (6 M) and 12 month (12 M) assessments (N = 99
| Outcome |
Arthroscopy N = 49 |
PHT N = 50 |
Arthroscopy - PHT | |||||
|---|---|---|---|---|---|---|---|---|
| n | Mean (SD or 95% CI) | n | Mean (SD or 95% CI) | Unadjusted difference | P-valuea | Adjusted difference (95% CI) | P-valuec | |
| iHOT-33 | ||||||||
| Baseline | 48 | 43.5 (17.6) | 50 | 40.4 (20.0) | ||||
| 6 month | 44 | 62.2 (21.2) | 42 | 57.5 (24.9) | ||||
| Change: 6 M-B | 44 | 18.6 (13.0–24.2) | 42 | 13.3 (7.2–19.3) | 5.4 | 0.194 | 5.2 (−2.7–13.2) | 0.196 |
| 12 month | 45 | 72.9 (21.8) | 46 | 56.8 (28.8) | ||||
| Change: 12 M-B | 45 | 29.6 (22.9–36.3) | 46 | 15.4 (8.8–22.1) | 14.2 | 0.003 | 14.7 (5.6–23.9) | 0.002 |
| EQ-5D-5L index score | ||||||||
| Baseline | 48 | 0.575 (0.206) | 50 | 0.544 (0.231) | ||||
| 6 month | 44 | 0.703 (0.177) | 41 | 0.682 (0.155) | ||||
| Change: 6 M-B | 44 | 0.121 (0.068–0.174) | 41 | 0.089 (0.033–0.145) | 0.032 | 0.405 | 0.026 (−0.035–0.087) | 0.398 |
| 12 month | 45 | 0.770 (0.156) | 46 | 0.653 (0.249) | ||||
| Change: 12 M-B | 45 | 0.194 (0.131–0.256) | 46 | 0.101 (0.033–0.169) | 0.093 | 0.046 | 0.106 (0.029–0.183) | 0.007 |
| EQ5D-VAS | ||||||||
| Baseline | 48 | 68.9 (16.3) | 50 | 68.8 (14.2) | ||||
| 6 month | 45 | 72.7 (16.8) | 42 | 71.7 (16.1) | ||||
| Change: 6 M-B | 45 | 3.7 (−1.5–9.0) | 42 | 1.3 (−4.4–7.0) | 2.4 | 0.530 | 1.6 (−4.9–8.1) | 0.627 |
| 12 month | 45 | 76.9 (15.2) | 46 | 74.7 (14.6) | ||||
| Change: 12 M-B | 45 | 7.9 (2.4–13.3) | 46 | 5.8 (1.0–10.6) | 2.1 | 0.570 | 2.1 (−3.7–7.9) | 0.470 |
| HOOS Pain | ||||||||
| Baseline | 47 | 59.4 (18.4) | 50 | 57.4 (18.9) | ||||
| 6 month | 45 | 74.0 (17.8) | 45 | 67.6 (23.5) | ||||
| Change: 6 M-B | 43 | 13.2 (7.0–19.4) | 45 | 10.9 (5.7–16.1) | 2.3 | 0.567 | 3.7 (−3.8–11.2) | 0.327 |
| 12 month | 41 | 83.9 (16.0) | 42 | 71.3 (19.9) | ||||
| Change: 12 M-B | 41 | 24.8 (17.7–32.0) | 42 | 11.1 (5.2–17.1) | 13.7 | 0.004 | 12.9 (5.4–20.5) | 0.001 |
| HOOS Symptom | ||||||||
| Baseline | 47 | 49.7 (17.5) | 50 | 50.7 (20.9) | ||||
| 6 month | 45 | 64.4 (19.7) | 45 | 59.8 (25.6) | ||||
| Change: 6 M-B | 43 | 14.4 (8.3–20.5) | 45 | 8.7 (3.5–13.8) | 5.8 | 0.149 | 5.3 (−2.3–12.9) | 0.168 |
| 12 month | 41 | 73.8 (18.8) | 42 | 63.8 (22.8) | ||||
| Change: 12 M-B | 41 | 23.2 (16.1–30.3) | 42 | 9.6 (3.4–15.8) | 13.5 | 0.005 | 11.7 (3.3–20.1) | 0.007 |
| HOOS ADL | ||||||||
| Baseline | 47 | 69.2 (18.0) | 50 | 65.9 (20.4) | ||||
| 6 month | 45 | 80.8 (18.2) | 45 | 75.0 (24.0) | ||||
| Change: 6 M-B | 43 | 11.1 (5.1–17.2) | 45 | 9.2 (4.7–13.6) | 2.0 | 0.591 | 3.1 (−3.9–10.1) | 0.377 |
| 12 month | 41 | 89.7 (14.3) | 42 | 76.6 (21.4) | ||||
| Change: 12 M-B | 41 | 20.4 (14.6–26.2) | 42 | 7.4 (2.4–12.3) | 13.0 | 0.001 | 13.0 (6.4–19.7) | 0.000 |
| HOOS Sport and Recreation | ||||||||
| Baseline | 47 | 47.9 (22.4) | 50 | 46.9 (23.6) | ||||
| 6 month | 45 | 61.1 (19.9) | 45 | 58.5 (27.9) | ||||
| Change: 6 M-B | 43 | 12.8 (6.0–19.6) | 45 | 12.5 (5.9–19.1) | 0.3 | 0.951 | 1.1 (−7.4–9.6) | 0.803 |
| 12 month | 41 | 75.2 (17.5) | 42 | 62.5 (25.4) | ||||
| Change: 12 M-B | 41 | 28.4 (20.7–36.0) | 42 | 13.2 (5.9–20.6) | 15.1 | 0.005 | 13.7 (4.9–22.4) | 0.003 |
| HOOS Quality of Life | ||||||||
| Baseline | 47 | 33.6 (16.1) | 50 | 30.1 (17.6) | ||||
| 6 month | 45 | 47.2 (24.2) | 45 | 42.2 (23.3) | ||||
| Change: 6 M-B | 43 | 13.4 (6.5–20.2) | 45 | 13.3 (8.4–18.3) | 0.0 | 0.993 | 0.8 (−7.4–9.1) | 0.845 |
| 12 month | 41 | 62.7 (25.3) | 42 | 46.0 (24.3) | ||||
| Change: 12 M-B | 41 | 29.3 (21.7–36.8) | 42 | 15.6 (8.4–22.9) | 13.6 | 0.010 | 14.9 (4.9–24.8) | 0.004 |
| MAX MRI alpha angle | ||||||||
| Baseline | 47 | 70.2 (11.9) | 49 | 70.6 (15.6) | ||||
| 12 month | 43 | 62.7 (16.9) | 41 | 69.2 (16.2) | 0.039b | |||
| Change: 12 M-B | 43 | −7.5 (−11.4 - -3.6) | 40 | −0.1 (−1.2–1.0) | −7.4 | 0.001 | −7.4 (−11.6 - -3.3) | 0.001 |
| Radiographic (Hip2Norm) Measures | ||||||||
| Total AP anterior coverage | ||||||||
| Baseline | 47 | 27.2 (8.2) | 50 | 24.7 (6.2) | ||||
| 12 month | 42 | 26.7 (5.9) | 43 | 25.2 (6.0) | ||||
| Change: 12 M-B | 42 | −0.2 (−2.1–1.7) | 43 | 0.9 (−1.4–3.2) | − 1.1 | 0.452 | 0.4 (−1.9–2.7) | 0.706 |
| Total AP posterior coverage | ||||||||
| Baseline | 47 | 47.4 (8.1) | 50 | 45.0 (8.3) | ||||
| 12 month | 42 | 47.0 (8.5) | 43 | 44.6 (8.8) | ||||
| Change: 12 M-B | 42 | −0.7 (−1.8–0.5) | 43 | −0.4 (−2.6–1.8) | −0.3 | 0.820 | 0.2 (−2.2–2.6) | 0.845 |
| Total Femur coverage | ||||||||
| Baseline | 47 | 82.4 (7.6) | 50 | 81.0 (7.3) | ||||
| 12 month | 42 | 79.8 (6.7) | 43 | 81.0 (6.7) | ||||
| Change: 12 M-B | 42 | −2.4 (−5.0–0.2) | 43 | 0.3 (−1.6–2.2) | −2.7 | 0.097 | −1.8 (−4.4–0.7) | 0.153 |
| LCE | ||||||||
| Baseline | 47 | 37.1 (5.4) | 50 | 34.7 (6.6) | ||||
| 12 month | 42 | 34.2 (6.2) | 43 | 34.0 (5.6) | ||||
| Change: 12 M-B | 42 | −2.9 (−4.3 - -1.5) | 43 | −0.4 (−1.4–0.7) | −2.5 | 0.005 | −1.8 (−3.5 - − 0.2) | 0.031 |
| Acetabular Index | ||||||||
| Baseline | 47 | 2.5 (4.2) | 50 | 4.7 (4.8) | ||||
| 12 month | 42 | 4.0 (5.0) | 43 | 5.4 (4.4) | ||||
| Change: 12 M-B | 42 | 1.2 (0.1–2.4) | 43 | 1.0 (−0.2–2.1) | 0.3 | 0.728 | -0.2 (−1.7–1.3) | 0.790 |
| ACM angle | ||||||||
| Baseline | 47 | 45.0 (2.5) | 50 | 44.7 (3.6) | ||||
| 12 month | 42 | 44.6 (2.8) | 43 | 44.7 (3.1) | ||||
| Change: 12 M-B | 42 | −0.3 (−1.1–0.5) | 43 | 0.0 (−0.8–0.9) | −0.3 | 0.598 | −0.2 (− 1.2–0.8) | 0.688 |
| Extrusion Index | ||||||||
| Baseline | 47 | 15.0 (4.5) | 50 | 17.0 (5.7) | ||||
| 12 month | 42 | 18.2 (5.2) | 43 | 17.4 (4.9) | ||||
| Change: 12 M-B | 42 | 3.3 (1.9–4.7) | 43 | 0.1 (−0.8–1.1) | 3.2 | 0.000 | 2.5 (0.9–4.0) | 0.002 |
| Retroversion Index | ||||||||
| Baseline | 47 | 11.3 (12.8) | 50 | 14.7 (14.4) | ||||
| 12 month | 42 | 9.3 (10.7) | 43 | 11.3 (14.3) | ||||
| Change: 12 M-B | 42 | −0.8 (−3.9–2.2) | 43 | −2.5 (−6.7–1.7) | 1.6 | 0.527 | 0.0 (− 4.6–4.6) | 0.997 |
iHOT-33 International Hip; Hip Osteoarthritis MRI Scoring System (HOAMS)
aPaired t-test
bWilcoxon rank-sum test
cBased on regression model including adjustment for baseline