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Radioprotective functions of older Itch−/− bone marrow cells
| Donor cells | Itch+/+ donor | Itch−/− donor |
|---|---|---|
| 0 | 0/10 | 0/10 |
| 1 × 102 | 0/10 | 0/10 |
| 1 × 103 | 0/10 | 2/10 |
| 5 × 103 | 0/10 | 8/10 |
| 1 × 104 | 0/10 | 10/10 |
| 5 × 104 | 5/10 | 10/10 |
| 1 × 105 | 8/10 | 10/10 |
Survival of lethally irradiated wild-type (CD45.1+) recipients of limiting numbers of bone marrow cells from 20-week-old Itch+/+ and Itch−/− mice; results are presented as number of surviving mice/total mice. Data are representative of two independent experiments.
