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. 2021 Aug 3;9:661272. doi: 10.3389/fcell.2021.661272

FIGURE 2.

FIGURE 2

Copy number profile and comparison from LC-WGS cfDNA and WES tumor biopsy. (A) Left track shows genome-wide copy number from two ID-NHL patients (FR-02-056 and FR-02-067 with the following median coverage for cfDNA 4.24X, 3.49X and for WES tumor biopsy 216X, 211X, respectively). Right track shows cfDNA tumor fraction (TF) computed using ichorCNA and Tumor purity calculated using ABSOLUTE. (B) Left track shows genome-wide copy number from a 1p19q codeleted glioma patient FR-03-057 with the following median coverage for 4.30X for cfDNA and 166 X for WES tumor biopsy. Right track shows Spearman rank correlation between LC-WGS cfDNA and WES tumor biopsy (see Materials and Methods).