TABLE 3.

VA Differences Across the PDV and Liver

Item	Baseline (n = 22)	Following Surgery (n = 22)	P Value
Bile salts (µmol/L)
ΔPDV	4.3 [+2.2 to +8.4]†	+6.7 [+4.2 to +11.8]†	0.029
ΔLiver *
0.7 vs. 0.3	−2.5 [−5.5 to −1.2]†	−3.4 [−8.2 to −2.7]†	<0.001
0.9 vs. 0.1	−3.5 [−7.3 to −1.9]†	−4.7 [−10.5 to −3.6]†	<0.001
FGF19 (ng/mL)
ΔPDV	+0.02 [+0.01 to +0.03]†	+0.02 [0.00 to +0.03]‡	0.633
ΔLiver *
0.7 vs. 0.3	0.00 [−0.01 to +0.03]	+0.01 [−0.01 to +0.01]	0.824
0.9 vs. 0.1	−0.00 [−0.01 to +0.02]	+0.01 [−0.02 to +0.01]	0.799

Data are expressed as median [IQR]. Positive ΔVA indicates release by the organ/area, and a negative ΔVA indicates uptake. P values in bold are less than 0.05 and represent significant statistical differences.

^*ΔVA across the liver is calculated assuming different ratios (portal vs. arterial) of blood supply to the liver. Symbols indicate significance against theoretical zero.

^† P < 0.001 in comparison of VA differences before and after liver resection.

^‡ P < 0.01 in comparison of VA differences before and after liver resection.