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. 2021 Jul 16;13(7):e16429. doi: 10.7759/cureus.16429

Table 3. Univariate and multivariate analyses for overall survival.

BMI, body mass index; HR, hazard ratio; NACT; neoadjuvant chemotherapy; NLR, neutrophil-to-lymphocyte ratio; PDS; primary debulking surgery; FIGO: International Federation of Gynecology and Obstetrics; CA-125: cancer antigen-125; LG includes endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma, and low-grade serous carcinomas; HG includes high-grade serous carcinomas.

Characteristics Category Univariate Multivariate
P-value HR (95% CI) P-value
Age ≥47 vs. <47 years 0.712 0.65 (0.32-1.32) 0.230
Parity Multiparous vs. nulliparous 0.031 2.32 (1.11-4.84) 0.025
Menopausal status Postmenopause vs. premenopause 0.927 - -
BMI ≥24.0 vs. <24.0 kg/m2 0.795 - -
Serum CA-125 levels ≥112.0 vs. <112.0 U/mL 0.662 - -
Comorbidity Yes vs. no 0.749 - -
Upfront primary treatment NACT vs. PDS 0.657 - -
Ascites Yes vs. No 0.284 1.05 (0.53-2.07) 0.900
FIGO stage Advanced vs. early 0.507 - -
Surgical debulking status Optimal vs. suboptimal 0.944 - -
Histological subtype HG vs. LG 0.470 1.22 (0.57-2.60) 0.615
Pretreatment NLR ≥1.93 vs. <1.93 years 0.013 2.23 (1.08-4.61) 0.031