Figure 1.

The experimental time line of the study. Three sets of animals were used for this study. C57BL/6 mice received HI procedure using the Vannucci model on postnatal day 9 (p9). The serum samples were collected at 6 h and 24 h after HI for 24S-HC measurement. Histology, brain MRI, and the behavioral testing were performed at indicated postnatal (p) day (s) (OF: open field; NOR: novel object recognition; ROD: rotarod; MBP: myelin basic protein; IHC: immunohistochemistry; LFB: luxol fast blue). The animal numbers for sham and HI were listed for each set of experiment. HI: hypoxia-ischemia; MRI: magnetic resonance imaging.