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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Nat Genet. 2021 May 24;53(6):770–777. doi: 10.1038/s41588-021-00873-4

Figure 1. Comparing single-gene expression models on scRNA-seq data.

Figure 1.

(a) Example fits of different expression models, corresponding to different observation models, to observed data at a single gene. (b) Fraction of genes in biological data sets with strong evidence for a point-Gamma expression model over a Gamma model, and (c) examples of four genes showing strong evidence in an in silico mixture of T cells and B cells. (d) Fraction of genes with strong evidence in favor of a unimodal expression model over a Gamma model, and (e) an example of a gene showing strong evidence (PPBP in PBMCs). (f) Fraction of genes with strong evidence in favor of a fully non-parametric expression model over a unimodal non-parametric model, and (g) an example of a gene showing strong evidence (RPS4Y1 in iPSCs).