Table 5.

Parasitic loads of transmitting and non-transmitting T. cruzi seropositive mothers. Data from Rendell and colleagues are not reported here due to overlapping data with Kaplinski and colleagues (Kaplinski et al., 2015; Rendell et al., 2015).

Study	Transmitting mothers		Non-transmitting mothers		Reported statistic	Method
	N	Parasitic load (mean ± standard deviation)	N	Parasitic load (mean ± standard deviation)
Bern et al., 2009	10	85.6 ± 109.7 eP/mL	144	20.9 ± 84.3 eP/mL	P < 0.01	qPCR with primer set Cruzi 1 and Cruzi 2
Kaplinski et al., 2015 *	31	97.5 ± 138.5 eP/mL	41	9.9 ± 22.7 eP/mL	P < 0.0001	qPCR with primer set Cruzi 1 and Cruzi 2
Bua et al., 2012	20	11 ± 2.7 eP/mL	20	1.8 ± 0.5 eP/mL	P < 0.05	SYBR GreenER qPCR SuperMix Universal kit
Buekens et al., 2018	11	8.6 ± 11.8 eP/mL	336	5.7 ± 7.4 eP/mL	–	qPCR with primer sets Tcz1-Tcz2 and 121–122
Brutus et al., 2010 †	–	26.4 ± 22.3 p/mm3	–	3.5 ± 8.4 p/mm3	P = 0.001	Microscopic examination of parasites in buffy coat of heparinized microhematocrit tubes

eP/mL: equivalent parasites per milliliter. p/mm³: parasites per cubic millimeter.

^*Means and standard deviations were estimated from the medians and interquartile ranges (See Methods).

^†This study included 147 T. cruzi seropositive mothers but did not report the number of transmitting and non-transmitting women.