TABLE 1.

Overview of injection routes, vectors, and dosage used.

Study	Vectors	Injection route	Volume (μl)	Total dose (GC/mouse)	Titer (GC/ml)
Comparison of capsids at a low dose	AAV5-GFP AAV5-PhP.B-GFP AAV9-GFP AAV9-PhP.B-GFP	IV	200/25 gr	2,5 × 1011	1 × 1012
AAV9-PhP.B transduction of CNS	AAV9-PhP.B-GFP	IV	200/25 gr	4 × 1012	1,6 × 1013
AAV5 vs. AAV9-PhP.B	AAV5-miRNA	IV	160/20 gr*	4 × 1012	2,7 × 1013
	AAV9-miRNA	IStr	4 (2/hemisphere)	1 × 1011	2,7 × 1013

*Mice were 6 weeks old at the start of the experiment.