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. 2021 Aug 9;1(1):15–37. doi: 10.1021/acsnanoscienceau.1c00009

Figure 4.

Figure 4

Schematic representation of potential cellular binding partners of HCV core protein MoRFs. The core fragments used in yeast two-hybrid screening (black bars) have MoRFs (gray rectangles). Each core fragment has three cellular binding partners (ovals). The split luciferase assay is normalized to GFP controls. DDX3X, NPM1, TRIP11, and RILPL2 were identified in the luciferase assay. MoRF: molecular recognition features. LD: lipid droplet. Y2H: yeast two-hybrid. CF: core fragment. Ovals: cellular binding partners.