TABLE 1.
Observed prevalence of pfmdr1 polymorphisms and allele combinations in Huye, Rwanda, in 2010 and in 2018/2019
| pfmdr1 allele or allele combinationa | 2010 (13), n = 104 [% (n)] | 2018 and 2019,b n = 212 [% (n)] |
|---|---|---|
| 86Y | 39.4 (41) | 3.8 (8)* |
| 184F | 51.9 (54) | 53.8 (114) |
| 1246Y | 12.5 (13) | 2.4 (5)* |
| N86-Y184-D1246 | 18.3 (19) | 44.3 (94)* |
| N86-184F-D1246 | 38.5 (40) | 50.0 (106) |
| 86Y-Y184-D1246 | 23.1 (24) | 1.9 (4)* |
| 86Y-184F-D1246 | 7.7 (8) | 1.4 (3)* |
| 86Y-Y184-1246Y | 5.8 (6) | 0.5 (1)* |
| N86-184F-1246Y | 2.3 (3) | 1.9 (4)* |
| 86Y-184F-1246Y | 2.3 (3) | 0 |
| N86-Y184-1246Y | 1.0 (1) | 0 |
a
Mutations are presented in boldface.
b
*, significantly different from the respective proportion in 2010.