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. 2021 Mar 20;144(7):2166–2175. doi: 10.1093/brain/awab092

Figure 2.

Figure 2

Contributions of‘ combinations of the pathological indices to cognitive decline (model derived slopes). Alzheimer’s disease (AD) = neurodegenerative pathologies related to Alzheimer’s disease, i.e. global Alzheimer’s disease pathology, amyloid-β and PHFtau tangles; CVD = cerebrovascular diseases, i.e. gross infarcts, microscopic infarcts, atherosclerosis, arteriolosclerosis, cerebral amyloid-β angiopathy; non-Alzheimer’s disease (non-AD) = neurodegenerative pathologies, i.e. Lewy bodies, hippocampal sclerosis and LATE-NC.