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The classification of major histocompatibility complex (MHC) molecules and main molecules in maternal-fetal immunity. MHC includes MHC class I and II molecules. Classic MHC class I molecules include human leukocyte antigen (HLA)-A, HLA-B, and HLA-C. The non-classic MHC class I molecules include HLA-E, HLA-F, and HLA-G. MHC class II molecules include HLA-DR, HLA -DP, HLA -DQ. HLA-C, HLA-E, and HLA-G play a significant role in immune tolerance in the maternal-fetal interface.
